Leneva® Treatment For Corns and Calluses

At Restore Podiatry, Dr. Bhela uses the breakthrough, non-surgical Leneva® injections to treat ball of foot pain, corn and callus discomfort, and diabetic ulcers.
Leneva® is a brand new fat grafting system introduced in the United States in November 2019. Leneva® injections are a non-invasive way to treat foot pain caused by corns, calluses, and ulcerations due to loss of fat padding. As we age, the fat pad within our feet shifts or thins, causing increased pressure points and pain with every step we take. This all-natural injectable product consists of sterilized human fat tissue (called adipose tissue) that is placed within a cellular matrix.

Non-surgical treatment for Painful Corns, Calluses and Fat Pad Atrophy due to Fat Pad Loss

We offer a minimally invasive injection to treat foot pain caused by painful corns or calluses, pain in the ball of the foot or heel and even ulcerations due to loss of fat pad. It is very common in older people as we age, the amount of fat pad may be diminished or fat pad shifts due to foot deformity such as hammertoe and bunion deformity or repeated steroid injections for plantar fasciitis. The fat pad diminished down, causing less gap between prominent bone and skin and pain with every step we take.


Leneva is a first-of-its-kind human adipose tissue for tissue reconstruction. As an all-natural extracellular matrix, Leneva is a safe, natural, off-the-shelf solution that has multiple clinical applications including, but not limited to:

  • Calluses and Corns
  • Ball of Foot Pain
  • Pressure Area (Bunions)
  • Diabetic Foot Ulcers
  • Pressure Ulcers
  • Fat Pad Restoration Procedures

Leneva Allograft Adipose Matrix is made of fat tissue which is intended for the replacement of damaged or inadequate integumental adipose tissue matrix. Leneva Allograft Adipose matrix also be used for the reinforcement or supplemental support in underlying adipose tissue matrix as the result of damage or naturally occurring defects. This process utilized preserves the extracellular matrix of the allograft adipose. The resulting allograft serves as a framework to support the cellular repopulation and vascularization at the surgical site.

What Is Leneva® For Corns and Calluses?

Leneva® is an allograft adipose matrix derived from donated human tissue used for tissue reconstruction. It is a safe and clinically proven solution to help with foot pain without steroid injections or surgery. Leneva® is also FDA-approved.
When inserted under a pressure point, Leneva® not only cushions the area, but also provides a scaffolding for your body to build new fat cells at the site of the injection. This combination of grafted fat plus your own new fat cells creates a stable cushion that can provide comfort over many months to years.
Fat pad loss under the ball of the foot and heel is a common cause of pain in many patients, leaving them feeling like they are walking on rocks with each step. Patients with significant fat pad loss complain about extreme forefoot pain, the inability to tolerate walking barefoot on hard surfaces, painful recurrent calluses, and even open blisters or wounds. Leneva® injections help patients regrow the fat they once had on their feet.

What Is Leneva And How Can It Help Me?

Leneva is an off-the-shelf injectable human adipose tissue that is designed to support your body’s own tissue regeneration process. Leneva undergoes strict processing designed to maintain the structural integrity of the tissue without sacrificing quality and sterility. This process allows for retention of key matrix proteins such as Collagen IV and Collagen VI as well as adipogenic and angiogenic factors leptin, adiponectin, FGF-2, and VEGF, while successfully removing residual lipid, cellular fragments, and DNA content. Leneva may be used for the replacement of damaged or inadequate integumental adipose tissue matrix, or for the reinforcement or supplemental support in underlying adipose tissue matrix as the result of damage or naturally occurring defects.

close up of the bottom of a person's feet

How Do I Know It’s Safe?

MTF Biologics’ strict donor criteria is designed by medical experts to ensure quality and safety. Available relevant medical records are evaluated by our MTF Biologics Physicians to determine donor suitability. This comprehensive review indicates that the donor suitability criteria is in compliance with FDA and AATB regulations, therefore deeming the tissue eligible for transplantation.

 Possible adverse effects of using donated human tissue include, but are not limited to:

  • Local or systemic infection
  • Dehiscence and/or necrosis due to poor revascularization
  • Specific or nonspecific immune response

How Often Is Leneva® Done?

After the first treatment, patients are seen by Dr. Bhela for a follow-up in 4-6 weeks. It can take about 3 months for the injection to fully incorporate. Depending on activity level, the average length of time that the injection lasts is about 2 years.


All insurance companies do NOT typically pay for LENEVA® injections. The price of the Leneva covers the cost of the injectable, processing, local anesthesia, and the actual procedure of injecting the Leneva and 1 post-visit care at 4 to 6 weeks.

$1200 for single callus or corn (1.5 cc of LENEVA®)

$2000 for heel (3 cc of LENEVA®)